Dr. Steven Potkin


Dr. Steven Potkin

Dr. Potkin received his M.D. from Washington University in St. Louis, MO. He completed his Residency in Psychiatry at Duke University, Durham, NC.

Dr. Potkin was a Clinical Associate, Laboratory of Clinical Psychopharmacology, NIMH, St. Elizabeth's Hospital, Washington, D.C., a Research Psychiatrist, Adult Psychiatry Branch, NIMH, Washington, D.C., and Scientific Director for International Affairs (acting), Office of the Associate Administrator for International Affairs; Alcohol, Drug Abuse and Mental Health Administration in Rockville, MD.

He is presently Assistant Chief (acting), Center for Studies of Schizophrenia, and Head, Center for Studies of Schizophrenia at NIMH.

He is also presently a Professor, Department of Psychiatry and Human Behavior, Director of Research, Department of Psychiatry and Human Behavior, and the Director of the Brain Imaging Center, all at the University of California, at Irvine. Dr. Potkin is a member of the UCSD-UCI GCRC Advisory Committee, and the Robert R. Sprague Director at the Brain Imaging Center, University of California, Irvine

Dr. Potkin has received the following honors and awards:

• Sol Ginsburg Fellowship, Group for the Advancement of Psychiatry (GAP), 1974-76

• A.E. Bennett Clinical Science Research Award from the Society of Biological Psychiatry, 1981

• NIMH Foreign Work Study Fellowship, 1981-83

• Moroccan-American Scientific Cooperation Commission Scholar, 1985

• World Health Organization, U.S. Center for Research & Training in Biological Psychiatry, Deputy Director and Coordinator, 1988.

• California Alliance for the Mentally Ill Outstanding Psychiatrist, 1990

• Listed in The Best Doctors in America, Woodward/White Inc. 1994 and 1998

•Recipient of the Riley Public Service Award, Mental Health Association of Orange County. 1999

• NAMI Exemplary Psychiatrist Award, 1992 and 2000

• Mitchell B. Balter Award recipient, 2001

• American Psychiatric Association Distinguished Fellow, 2003

• Function BIRN – U24, NIH/NCRR (S.G. Potkin, PI), 2006-2010. This project will develop technology and methods to conduct multi site functional imaging studies, and to produce a knowledge base that would not otherwise be available through single-site imaging studies. The technology includes the development and refinement of multi-site, functional imaging protocols using robust cognitive tasks; the development and refinement of algorithms to reduce inter-site variability; the use of federated, distributed databases and storage; flexible and robust image processing software integrated with these databases and storage infrastructure; tools for data querying across the distributed databases to extract subset of data from multiple sources; and the development of both classical statistical and data mining methods to reveal the patterns of imaging, clinical, and behavioral data which differentiate important population clusters. Role: PI of the overall consortium

• Transdisciplinary Imaging Genetics Center – P20, NIH (S.G. Potkin, PI), 2004-2007. This Center is focuses on developing robust and sensitive methods of combining genetic and neuroimaging data in analysis and visualization, for a more complete understanding of genetic influences on cognitive processing.
Role: PI

• National Alliance for Medical Imaging Computing (RFA Title: National Centers for Biomedical Computing), NIH, (S.G. Potkin, UCI PI & Core 3 Co-PI), 2004-2007. This project is a multi-institutional, interdisciplinary team of computer scientists, software engineers, and medical investigators who develop computational tools for the analysis and visualization of medical image data. Dr. Potkin’s role in the NAMIC is to lead work in schizophrenic circuitry, exploring the function and dysfunction of various cortical areas as measured in PET, DTI and fMRI datasets in comparison to circuitry measurements and given genetic hypotheses.
Role: UCI site PI

• Morphometry Biomedical Informatics Research Network, NIH, NCRR, (S.G. Potkin, PI), 2004-2009. This project focuses on collecting imaging data, upload data to BIRN infrastructure; develop software for BIRN. Morphometry BIRN participants are examining neuroanatomical/imaging (MRI) correlates of neuropsychiatric illnesses in such disorders as unipolar depression, mild Alzheimer’s disease, and mild cognitive impairment.
Role: UCI site PI

• Genomic Studies in Bipolar and Major Depression, NIMH - SILVIO O. CONTE CENTER GRANT Co-I, (W. Bunney PI), 2004-2009. This research program is focused on the discovery of etiologically relevant differentially expressed genes in postmortem brain tissue from depressed patients and individually matched controls utilizing the new cDNA microarray high throughput technology. Dr. Potkin is responsible for the post-mortem brain bank and is a co-investigator.

• Sensory Gating in Schizophrenia: Multiple Measures, NIH, 2001-2005, (J. Patterson, PI). Topical and quantitative EEG measures in normal subjects and patients with schizophrenia are being obtained to characterize the sensory gating abnormalities in schizophrenia. These EEG data are combined with clinical and neurocognitive assessments.

He is the author or co-author of dozens or peer-reviewed publications including articles in the Journal of Clinical Psychiatry and the Journal of Neuroscience.

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Dr. Steven Potkin
Dr. Steven Potkin